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Donepezil hydrochloride

Overview
Catalog # bs-76222c-250mg
Product Name Donepezil hydrochloride
Specifications
Storage Buffer Powder
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 120011-70-3

Molecular formula: C24H29NO3 . HCl

Molecular weight: 379.5 . 36.5

Purity: >98% (T)

Appearance: White to off-white crystalline powder.

Solubility: Soluble in water (20 mg/ml). Sparingly soluble in DMSO (1mg/ml), methanol or ethanol.

InChiKey: XWAIAVWHZJNZQQ-UHFFFAOYSA-N

SMILES: O=C1C2=CC(OC)=C(OC)C=C2CC1CC3CCN(CC4=CC=CC=C4)CC3.Cl

SMILES: Cl.COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1
Description Potent non-competitive reversible acetylcholinesterase inhibitor that readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine. Displays >1000-fold selectivity for acetylcholinesterase (AChE) over butyrylcholinesterase (BuChE). It is commonly used in the treatment of Alzheimer's disease to improve cognition, memory and behavior.