IR-783

Overview
Catalog #	bs-76466c-250mg
Product Name	IR-783
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 115970-66-6 Molecular formula: C38H46ClN2NaO6S2 Molecular weight: 749.37 Purity: >98% (HPLC) Appearance: Dark red to brown powder. Solubility: Soluble in water or methanol. InChiKey: QQIQAVJARACLHE-UHFFFAOYSA-M SMILES: ClC1=C(/C=C/C2=[N+](CCCCS(=O)(O[Na])=O)C3=C(C=CC=C3)C2(C)C)CCC/C1=C\C=C4N(CCCCS(=O)([O-])=O)C(C=CC=C5)=C5C/4(C)C SMILES: [Na+].CC1(C)C(=CC=C2CCCC(C=CC3=[N+](CCCCS([O-])(=O)=O)C4=CC=CC=C4C3(C)C)=C2Cl)N(CCCCS([O-])(=O)=O)C2=CC=CC=C12
Description	IR-783 is a functional laser and near-IR (NIR) dye. Spectral data: Absorption lambdamax=783nm (MeOH). IR-783 has been shown to be a dye that exhibits imaging, cancer targeting and anticancer properties. Useful optical probe for NIR imaging of tumors, shown to accumulate in the mitochondria and lysosomes of cancer cells. IR-783 inhibits cell viability and induces mitochondrial apoptosis in human breast cancer cells and induces cell proliferation in a dose- and time-dependent manner by inducing cell cycle arrest at the G0/G1 phase.