Limonin
| Overview | |
| Catalog # | bs-76490c-50mg |
| Product Name | Limonin |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 1180-71-8 Molecular formula: C26H30O8 Molecular weight: 470.51 Purity: >98% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in DMSO (10mg/ml) or DMF (20mg/ml). InChiKey: KBDSLGBFQAGHBE-MSGMIQHVSA-N SMILES: O=C1[C@@]2(C)[C@@]34O[C@@H]3C(O[C@@H](C5=COC=C5)[C@]4(C)CC[C@]2([H])[C@]67[C@](C1)([H])C(C)(C)O[C@@]6([H])CC(OC7)=O)=O SMILES: [H][C@]12CC(=O)OC[C@@]11[C@@]([H])(CC(=O)[C@]3(C)[C@]1([H])CC[C@@]1(C)[C@@H](OC(=O)[C@H]4O[C@@]314)C1=COC=C1)C(C)(C)O2 |
| Description | Limonin is the first described limonoid, which are naturally occurring tetranortriterpenoids that impart bitter flavor in citrus fruits. Compounds belonging to this group have reported anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal, anti-malarial, anti-microbial, anti-HIV, anti-inflammatory, antinociceptive and neuroprotective activity. Shown to inhibit arginase I and II and P-glycoprotein. May be used in assays as control, standard or competitor, or in studies on the physiology, metabolism and biosynthesis of limonin. |