Tetra-O-methylscutellarein
| Overview | |
| Catalog # | bs-76565c-1mg |
| Product Name | Tetra-O-methylscutellarein |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 1168-42-9 Molecular formula: C19H18O6 Molecular weight: 342.3 Purity: >95% (HPLC) Appearance: White to yellow powder. Solubility: Soluble in DMSO (20mg/ml) or chloroform. InChiKey: URSUMOWUGDXZHU-UHFFFAOYSA-N SMILES: O=C(C=C(C1=CC=C(OC)C=C1)O2)C3=C2C=C(OC)C(OC)=C3OC SMILES: COC1=CC=C(C=C1)C1=CC(=O)C2=C(OC)C(OC)=C(OC)C=C2O1 |
| Description | Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-kappaB pathway. It suppressed IkappaB kinase complex alpha/beta (IKKalpha/beta) and Inhibitory-kappa-B-alpha (IkappaBalpha), inhibiting p65 translocation and thereby suppressing COX-2 and iNOS expression. This compound is modulating bacterial resistance to antimicrobial drugs most probably via efflux pump inhibition. It also showed anti-mutagenic activity. |
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