Medetomidine HCl

Overview
Catalog #	bs-76571c-10mg
Product Name	Medetomidine HCl
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 86347-15-1 Molecular formula: C13H17ClN2 Molecular weight: 236.75 Purity: >98% Appearance: White to off-white powder. Solubility: Soluble in water (20mg/ml) or DMSO (20mg/ml). InChiKey: VPNGEIHDPSLNMU-UHFFFAOYSA-N SMILES: CC1=CC=CC(C(C)C2=CNC=N2)=C1C.Cl SMILES: Cl.CC(C1=CNC=N1)C1=C(C)C(C)=CC=C1
Description	Medetomidine is an imidazole derivative. It acts as a potent selective agonist of alpha2-adrenoceptors (Ki=1.08nM vs. 1750nM for alpha1-adrenoceptors). Through its effect on alpha2-adrenoceptors, medetomidine has sedative, antinociceptive, hypotenisve, bradycardic, anxiolytic, analgesic and hypothermic actions. Its effects on pain are additive or synergistic with fentanyl-type opioids. The effects of medetomidine are effectively countered by alpha2-adrenoceptor antagonists, like atipamezole. Selective alpha2-adrenoceptor agonists, including medetomidine, have anesthetic sparing properties, greatly reducing the dose of anesthetic required following premedication with the alpha2-adrenoceptor agonist.