Nadolol

Overview
Catalog #	bs-76603c-1g
Product Name	Nadolol
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 42200-33-9 Molecular formula: C17H27NO4 Molecular weight: 309.4 Purity: >98% (GC) Appearance: White to off-white powder. Solubility: Soluble in DMSO (20mg/ml) or DMF. InChiKey: VWPOSFSPZNDTMJ-UCWKZMIHSA-N SMILES: O[C@H]1[C@@H](O)CC2=C(OCC(O)CNC(C)(C)C)C=CC=C2C1 SMILES: CC(C)(C)NCC(O)COC1=CC=CC2=C1CC(O)C(O)C2
Description	Nadolol is a polar and hydrophilic, non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. It is a long-acting beta-blocker, which displays activity against beta-1 and beta-2 receptors. It has a preference for beta-1 receptors, which are predominantly located in the heart, thereby inhibiting the effects of catecholamines and causing a decrease in heart rate and blood pressure. Nadolol's inhibition of beta-1 receptors in the heart and kidney leads to its effects on lowering blood pressure. Its inhibition of beta-2 receptors, which are mainly located in the bronchial smooth muscle of the airways, leads to airway constriction similar to that seen in asthma.