Ononin

Overview
Catalog #	bs-76661c-1mg
Product Name	Ononin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at RT.
Target
Product Information	CAS Number: 486-62-4 Molecular formula: C22H22O9 Molecular weight: 430.4 Purity: >98% (HPLC) Appearance: White powder. Solubility: Soluble in DMSO (10mg/ml). InChiKey: MGJLSBDCWOSMHL-MIUGBVLSSA-N SMILES: O[C@H]1[C@H](OC2=CC=C(C(C(C3=CC=C(OC)C=C3)=CO4)=O)C4=C2)O[C@H](CO)[C@@H](O)[C@@H]1O SMILES: COC1=CC=C(C=C1)C1=COC2=CC(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=CC=C2C1=O
Description	Ononin is a glycoside isoflavone that has been found in soybeans. It has anti-inflammatory activity by inhibiting the NF-kappaB and MAPK pathways and neuroprotective properties. Ononin inhibits LPS-induced production of nitrite, prostaglandin E2 and the pro-inflammatory cytokines IL-1beta, IL-6, and TNF-alpha by RAW 264.7 macrophages. It also inhibits glutamate-induced toxicity in rat adrenal PC12 cells.