SP-600125
| Overview | |
| Catalog # | bs-82020c-10mg |
| Product Name | SP-600125 |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | RT |
| Target | |
| Product Information | Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50’s range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo. |
| Description | CAS Number: 129-56-6 Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one Molecular weight: 220.23 Formula: C14H8N2O Solubility: DMSO (22 mg/ml) Ethanol (2 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC NMR conforms |
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