A-803467

Overview
Catalog #	bs-82045c-10mg
Product Name	A-803467
Specifications
Storage Buffer	white solid (MP = 128-130°C)
Storage Condition	RT
Target
Product Information	Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively.
Description	CAS Number: 944261-79-4 Chemical Name: 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide Molecular weight: 357.80 Formula: C19H16ClNO4 Solubility: DMSO (15 mg/ml) Ethanol (2 mg/ml) Physical Properties: white solid (MP = 128-130°C) Purity: 98% by TLC [50% ethyl acetate in hexanes, Rf = 0.58] NMR Conforms