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Mirin

Overview
Catalog # bs-82048c-5mg
Product Name Mirin
Specifications
Storage Buffer Tan solid
Storage Condition -20°C
Target
Product Information Mirin is an inhibitor of the Mre11-Rad50-Nbs1(MRN) complex (IC50 = 12 µM for inhibition of ATM activity), part of the MRN-ATM(ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Description CAS Number: 299953-00-7

Chemical Name: 5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one

Molecular weight: 220.25

Formula: C10H8N2O2S

Solubility: DMSO (30 mg/ml)

Physical Properties: Tan solid

Purity: 98% by TLC, NMR Conforms