Sivelestat

Overview
Catalog #	bs-82069c-5mg
Product Name	Sivelestat
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-κB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4.
Description	CAS Number: 127373-66-4 Chemical Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium Molecular weight: 456.45 Formula: C20H21N2O7 Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC