Garcinol
| Overview | |
| Catalog # | bs-82185c-10mg |
| Product Name | Garcinol |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7µM and PCAF IC50=5µM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2 |
| Description | CAS Number: 78824-30-3 Chemical Name: Molecular weight: 602.80 Formula: C38H50O6 Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Yellow solid Purity: >95% |
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