Wiskostatin
| Overview | |
| Catalog # | bs-82194c-5mg |
| Product Name | Wiskostatin |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | RT |
| Target | |
| Product Information | A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4. |
| Description | CAS Number: 253449-04-6 Chemical Name: 1-(3,6-Dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol Molecular weight: 426.15 Formula: C17H18Br2N2O Solubility: DMSO (30 mg/ml) Ethanol (10 mg/ml) Physical Properties: White solid Purity: 98% by TLC [9:1 CH2Cl2/CH3OH Rf = 0.16] NMR (Conforms) |
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