LYS6K2

Overview
Catalog #	bs-82220c-5mg
Product Name	LYS6K2
Specifications
Storage Buffer	Yellow solid
Storage Condition	RT
Target
Product Information	A selective inhibitor of the p70 ribosomal S6 kinase (S6K)1. Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 μM with no activity at GSK3β and Erk1/2 at 10 μM2. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K2. Cell permeable.
Description	CAS Number: 1082949-67-4 Chemical Name: 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine Molecular weight: 445.42 Formula: C21H19F4N7 Solubility: DMSO (1 mg/ml) DMF (3 mg/ml) Physical Properties: Yellow solid Purity: 97% by HPLC, NMR (conforms)