R-59022

Overview
Catalog #	bs-82693c-5mg
Product Name	R-59022
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets).1 Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism.2 Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.3 Blocks filovirus internalization in host cells.4
Description	CAS Number: 93076-89-2 Chemical Name: 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one Molecular weight: 459.58 Formula: C27H26FN3OS Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)