SLU-PP-332
Applications
| Overview | |
| Catalog # | bs-82738c-10-mg |
| Product Name | SLU-PP-332 |
| Applications | Life Science |
| Specifications | |
| Conjugation | Unconjugated |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Background | Pan-agonist of the estrogen receptor-related receptors (EC50’s cell-based cotransfection/reporter assay: ERRα = 98 nM, ERRß = 230 nM, ERRγ = 430 nM) with highest potency for ERRα.1,2 SLU-PP-332 increased mitochondrial function and cellular respiration in a skeletal muscle cell line.2 It also increased fast oxidative skeletal muscle fibers (Type IIa) and exercise endurance in mice in an ERRα-specific manner. SLU-PP-332 activates an acute aerobic exercise genetic response via inducing the expression of DDIT4.2 |
| Application Dilution | |
| Life Science | N/A |
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