Lomeguatrib
| Overview | |
| Catalog # | bs-82759c-10mg |
| Product Name | Lomeguatrib |
| Specifications | |
| Storage Buffer | Off-white or beige solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7. |
| Description | CAS Number: 192441-08-0 Chemical Name: 2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purine Molecular weight: 326.17 Formula: C10H8BrN5O3S Solubility: DMSO (10 mg/ml) Physical Properties: Off-white or beige solid Purity: 98% by TLC NMR (Conforms) |
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