ERGi-USU

Overview
Catalog #	bs-82840c-10mg
Product Name	ERGi-USU
Specifications
Storage Buffer	Red or Orange solid
Storage Condition	-20°C
Target
Product Information	ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
Description	CAS Number: 1147-56-4 Chemical Name: 1-(2-Thiazolylazo)-2-naphthol Molecular weight: 255.30 Formula: C13H9N3OS Solubility: DMSO (>10 mg/ml) Physical Properties: Red or Orange solid Purity: 98% by TLC NMR (Confirms)