Lomerizine

Overview
Catalog #	bs-82848c-10mg
Product Name	Lomerizine
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Lomerizine is a clinically useful calcium channel blocker (L and T-type). It is used for the treatment of migraine headaches, however its antimigraine effects are believed to be due to its 5HT2A antagonistic effects.1 Lomerizine also displays anti-glaucoma effects via an increase in ocular circulation and protection of neuronal cells against retinal neurotoxicity with minimal cardiovascular effects.2 Lomerizine has also shown various other neuroprotective properties.3,4,5,6
Description	CAS Number: 101477-54-7 Chemical Name: 1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride Molecular weight: 541.46 Formula: C27H30F2N2O3·2HCl Solubility: DMSO (>45 mg/ml) and Ethanol (30 mg/mL) Physical Properties: White solid Purity: >98% by TLC, NMR (Conforms)