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Mitapivat

Overview
Catalog # bs-82875c-5mg
Product Name Mitapivat
Specifications
Storage Buffer Beige solid
Storage Condition -20°C
Target
Product Information Potent (AC50 = 29 nM PKR; 37 nM PKM2; 33 nM PKL) allosteric activator of pyruvate kinase.1 In clinical use for the treatment of hemolytic anemia2 and a potential agent for the treatment for ß-thalassemia3 and sickle cell anemia4.
Description CAS Number: 1260075-17-9

Chemical Name: N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide

Molecular weight: 450.56

Formula: C24H26N4O3S

Solubility: DMSO (>50 mg/ml)

Physical Properties: Beige solid

Purity: 99% by HPLC NMR (Conforms)