BT2

Overview
Catalog #	bs-83001c-10mg
Product Name	BT2
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	BT2 is an inhibitor of the mitochondrial branched-chain α-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 µM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 µM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2
Description	CAS Number: 34576-94-8 Chemical Name: 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid Molecular weight: 247.10 Formula: C9H4Cl2O2S Solubility: DMSO (>20 mg/ml) Physical Properties: Off-white solid Purity: 95% by TLC NMR (Conforms)