IM-12
| Overview | |
| Catalog # | bs-83094c-5-mg |
| Product Name | IM-12 |
| Specifications | |
| Conjugation | Unconjugated |
| Storage Buffer | White or off-white solid |
| Storage Condition | -20°C |
| Target | |
| Background | A potent and selective inhibitor of glycogen synthase kinase 3 (GSK-3) IC50=53 nM which induces neuronal differentiation.1 Activates the Wnt--catenin signaling pathway and attenuates tissue plasminogen activator-induced hemorrhagic transformation after acute ischemic stroke in animal models.2 Promoted hair follicle growth in vitro and antagonized the inhibition of hair follicles by dihydrotestosterone.3 Down-regulates Sox9 expression in limbal epithelial stem/progenitor cells leading to increased differentiation.4 |
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