UNC 0224

Overview
Catalog #	bs-83101c-1-mg
Product Name	UNC 0224
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	UNC0224 is a potent inhibitor of histone methyltransferases G9a / EHMT2 (IC50 = 15 nM) and GLP / EHMT1 (IC50 ~ 39 nM) but not SET7/9 and SET8.1-3 Has been employed, as part of a small molecule cocktail, to reprogram somatic cells to pluripotent stem cells.4
Description	CAS Number: 1197196-48-7 Chemical Name: 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine Molecular weight: 485.68 Formula: C26H43N7O2 Solubility: DMSO (50 mg/ml) Physical Properties: White to off-white solid Purity: >98% by TLC NMR (Conforms)