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AdipoRon

Overview
Catalog # bs-83216c-50mg
Product Name AdipoRon
Specifications
Storage Buffer White solid
Storage Condition RT
Target
Product Information A novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 μM respectively1. Displayed similar effects to adiponectin in muscle and liver such as activation of PPARα and AMPK signaling pathways. It also reversed insulin resistance and glucose intolerance in mice on a high-fat diet. It ameliorated diabetes in a genetically obese mouse model and prolonged the shortened lifespan of db/db mice on a high-fat diet1. Active in vivo.
Description CAS Number: 924416-43-3

Chemical Name: Adiponection agonist

Molecular Weight: 428.54

Formula: C27H28N2O3

Solubility: DMSO (40 mg/ml) Ethanol (20 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR (Conforms)