Olaparib
| Overview | |
| Catalog # | bs-83259c-25mg |
| Product Name | Olaparib |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1 In a genetically engineered mouse model for BRCA1-associated breast cancer olaparib inhibited tumor growth and improved survival with no signs of toxicity.2 Synergizes with many other anticancer agents.3 Shows efficacy in colorectal cancers.4 Prevents house dust mite allergen-induced asthma in a mouse model.5 |
| Description | CAS Number: 763113-22-0 Chemical Name: PARP1 inhibitor Molecular Weight: 434.47 Formula: C24H23FN4O3 Solubility: DMSO (33 mg/ml) Ethanol (1.7 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms) |
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