Celastrol
| Overview | |
| Catalog # | bs-83269c-25mg |
| Product Name | Celastrol |
| Specifications | |
| Storage Buffer | Red Solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Displays potent antioxidant and anti-inflammatory activity. Inhibits NFκB (IC50=270 nM). It induces heat shock response and cytoprotection in various cells. Inhibits 20S proteasome chymotrypsin activity (IC50=2.5 μM). Induces autophagy by targeting AR/miR-101 in prostate cancer cells.4 Induces UPR-dependent cell death in cancer cells.5 Cell permeable. |
| Description | CAS Number: 34157-83-0 Chemical Name: Proteasome inhibitor Molecular Weight: 450.62 Formula: C29H38O4 Solubility: DMSO (45 mg/ml) Ethanol (30 mg/ml) Physical Properties: Red Solid Purity: 98% by TLC, NMR conforms |
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