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SB-216763

Overview
Catalog # bs-83288c-25mg
Product Name SB-216763
Specifications
Storage Buffer Orange solid
Storage Condition RT
Target
Product Information Potent and selective inhibitor of glycogen synthase kinase-1 (GSK-3) IC50=34.3 nM1. Acts at the ATP-binding domain. Displays protective effects in lung fibrosis mouse model2. Displays neuroprotective effects on cultured neurons3. Maintains mouse embryonic stem cells in a pluripotent state4. Cell permeable.
Description CAS Number: 280744-09-4

Chemical Name: GSK-3 inhibitor

Molecular Weight: 371.23

Formula: C19H12Cl2N2O2

Solubility: DMSO (25 mg/ml)

Physical Properties: Orange solid

Purity: 98% by TLC [1% CH3OH in CH2Cl2; Rf = 0.17] NMR (Conforms)