Ophiobolin

Overview
Catalog #	bs-83348c-1mg
Product Name	Ophiobolin
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Selectively inhibits the growth of cancer cells (IC50=0.4-4.3 M) over normal cells (IC50=20.9 M).1 Induces non-apoptotic cell death in glioblastoma cells and is active in an in vivo model.2 Covalently reacts with primary amines such as lysine side chains2 and phosphatidylethanolamine3 forming unique pyrrole adducts. Induces ER stress4, paraptosis4 and autophagy5.
Description	CAS Number: 4611-05-6 Chemical Name: Autophagy inducer / Anticancer Molecular Weight: 400.55 Formula: C25H36O4 Solubility: DMSO (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)