NVS-STG2
| Overview | |
| Catalog # | bs-83378c-25mg |
| Product Name | NVS-STG2 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice. |
| Description | CAS Number: 3030588-01-0 Chemical Name: Molecular glue STING agonist Molecular Weight: 427.54 Formula: C25H33NO5 Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms) |
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