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L-755,507

Overview
Catalog # bs-83379c-25mg
Product Name L-755,507
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information L-755,507 is a very potent (EC50 = 0.43 nM; IC50 = 13 nM) human ß3 adrenergic receptor agonist with >440-fold selectivity of ß1/2.1 It elicited lipolysis and metabolic rate elevation in rhesus monkeys.2 L-755,507 has been shown to increase homology-directed repair efficiency by 2- and 3-fold in CRISPR gene editing.3,4
Description CAS Number: 159182-43-1

Chemical Name: ß3 adrenergic agonist / CRISPR efficiency enhancer

Molecular Weight: 584.73

Formula: C30H40N4O6S

Solubility: DMSO (>25 mg/ml)

Physical Properties: Off-white solid

Purity: >98% by HPLC NMR (Conforms)