Necrosulfonamide
| Overview | |
| Catalog # | bs-83418c-25mg |
| Product Name | Necrosulfonamide |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5 |
| Description | CAS Number: 1360614-48-7 Chemical Name: Necroptosis inhibitor / MLKL inhibitor Molecular Weight: 461.47 Formula: C18H15N5O6S2 Solubility: DMSO (10 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms) |
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