Receive 30% off all Monoclonal IHC antibodies with code "MONO-IHC-30"! Offer valid for US customers and available internationally through distributors.

Ascochlorin

Overview
Catalog # bs-83434c-500ug
Product Name Ascochlorin
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5
Description CAS Number: 26166-39-2

Chemical Name: Mitochondrial cytochrome bc1 complex inhibitor

Molecular Weight: 404.93

Formula: C23H29ClO4

Solubility: DMSO (10 mg/ml)

Physical Properties: Off-white solid

Purity: >98% by HPLC NMR (Conforms)