Ascochlorin
Overview | |
Catalog # | bs-83434c-500ug |
Product Name | Ascochlorin |
Specifications | |
Storage Buffer | Off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5 |
Description | CAS Number: 26166-39-2 Chemical Name: Mitochondrial cytochrome bc1 complex inhibitor Molecular Weight: 404.93 Formula: C23H29ClO4 Solubility: DMSO (10 mg/ml) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms) |