XI-011

Overview
Catalog #	bs-83760c-5mg
Product Name	XI-011
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	XI-011 activates p53 by inhibiting expression of one of its negative regulators, MDM4 (MDMX).1 It was able to induce apoptosis in MCF-7 breast cancer cells. XI-011 acted synergistically with cisplatin in inducing apoptosis in head and neck cancer cells.2 It also induced apoptosis in several cervical cancer in vitro and in vivo.3 XI-011 displayed efficacy in treating lung fibrosis in an MDM4-dependent manner.4
Description	CAS Number: 59474-01-0 Chemical Name: (10-Methylanthracen-9-yl)methyl carbimidothioate hydrochloride Molecular Weight: 316.85 Formula: C17H16N2S·HCl Solubility: DMSO (25 mg/ml) Physical Properties: Yellow solid Purity: >98% by HPLC NMR (Conforms)