VU0810464

Overview
Catalog #	bs-83797c-5mg
Product Name	VU0810464
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	VU0810464 is potent (Kir3.1/3.2; GIRK1/2 EC50 = 165 nM) activator of G protein-gated inwardly-rectifying potassium channels (Kir3; GIRK).1,2 Displays selectivity for Kir3.1/3.2 versus Kir3.1/3.4 as well as selectivity for neuronal versus cardiac Kir3 channels. VU0810464 reduced stress-induced hyperthermia but not anxiety-related behavior in mice.
Description	CAS Number: 2126040-21-7 Chemical Name: 2-(3-Chloro-4-fluorophenyl)-N-(2-cyclohexyl-5-methylpyrazol-3-yl)acetamide Molecular Weight: 349.83 Formula: C18H21ClFN3O Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: >98% by TLC (NMR Conforms)