MUM1 Monoclonal Antibody

Overview
Catalog #	bsm-34186m
Product Name	MUM1 Monoclonal Antibody
Applications	IHC-P, IHC-F, IF
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Clonality	Monoclonal
Clone #	9H6
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at 2-8°C
Target
Gene ID	84939
Swiss Prot	Q2TAK8
Subcellular location	Cytoplasm, Cell membrane
Synonyms	EXPAND1; FLJ14868; FLJ22283; HSPC211; Melanoma associated antigen (mutated) 1; Melanoma ubiquitous mutated protein; MGC131891; MGC163315; MUM 1; MUM-1; MUM1_HUMAN; Mutated melanoma associated antigen 1; Mutated melanoma-associated antigen 1; Protein expandere; PWWP domain containing protein MUM1; PWWP domain-containing protein MUM1.
Background	Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). Also involved in secretory granule priming in insulin secretion (By similarity). Interacts with FBXO45 (via SRY domain); leading to the degradation of UNC13A by the proteasome (By similarity).
Application Dilution
IHC-P	1:200-400
IHC-F	1:100-500
IF