| Overview |
| bsm-34186m-pbs-only-100ul |
| MUM1 Monoclonal Antibody, PBS Only Conjugated |
| IHC-P, IHC-F, IF(IHC-P) |
| Human |
| Specifications |
| PBS Only |
| Mouse |
| Monoclonal |
| 9H6 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 84939 |
| Q2TAK8 |
| Cytoplasm, Cell membrane |
| EXPAND1; FLJ14868; FLJ22283; HSPC211; Melanoma associated antigen (mutated) 1; Melanoma ubiquitous mutated protein; MGC131891; MGC163315; MUM 1; MUM-1; MUM1_HUMAN; Mutated melanoma associated antigen 1; Mutated melanoma-associated antigen 1; Protein expandere; PWWP domain containing protein MUM1; PWWP domain-containing protein MUM1.
|
Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). Also involved in secretory granule priming in insulin secretion (By similarity). Interacts with FBXO45 (via SRY domain); leading to the degradation of UNC13A by the proteasome (By similarity).
|
| Application Dilution |
| IHC-P |
1:100-500 |
| IHC-F |
IHC-F1:100-500 |
| IF(IHC-P) |
IFIHC-P1:100-500 |
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