| Overview |
| bs-11270R |
| HSP56/FKBP52 Polyclonal Antibody |
| WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC |
| Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HSP56 |
| 1-100/459 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| Cytoplasm, Nucleus |
| Hsp 56; HSP binding immunophilin; HSP-binding immunophilin; Hsp56; N-terminally processed; 51 kDa FK506-binding protein; 52 kDa FK506 binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506 binding protein 4; FK506-binding protein 4; FKBP 4; FKBP 52; FKBP 59; FKBP-4; FKBP-52; FKBP4; FKBP4_HUMAN; FKBP51; FKBP52 protein; FKBP59; HBI; Immunophilin FKBP52; p52 antibody p59 antibody p59 protein; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP4; Peptidylprolyl cis trans isomerase; PPIase; PPIase FKBP4; Rotamase; T cell FK506 binding protein 59kD. |
| HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
| ICC |
1:100-500 |
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