GPR56 Polyclonal Antibody, Cy5.5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-11848R-Cy5.5
Product Name GPR56 Polyclonal Antibody, Cy5.5 Conjugated
Applications WB, FCM
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig, Horse, Rabbit
Specifications
Conjugation Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GPR56
Immunogen Range 275-350/693
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 9289
Swiss Prot Q9Y653
Subcellular location Cell membrane
Synonyms BFPP; DKFZp781L1398; EGF TM7 like; G protein coupled receptor 56; GPR 56 ; Polymicrogyria bilateral frontoparietal; TM7LN4; TM7XN1; TM7XN1 protein; GPR56_HUMAN; ADGRG1; Adhesion G-protein coupled receptor G1.
Background G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. G-protein coupled receptor 56 (GPR56), also designated TM7XN1 protein, contains one GPS domain. GPR56 plays an important role in cell-cell interactions and is widely expressed, with highest levels detected in brain, heart and thyroid gland. Defects in the gene encoding for GPR56 can cause bilateral frontoparietal polymicrogyria (BFPP) which is characterized by disorganized cortical lamination.
Application Dilution
WB 1:300-5000
FCM 1:20-100