P2RX1 Polyclonal Antibody, PBS Only Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-12107r-pbs-only-100ul |
| Product Name | P2RX1 Polyclonal Antibody, PBS Only Conjugated |
| Applications | WB, IHC-P, IF(IHC-P) |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PBS Only |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human P2RX1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | PBS (pH=7.4) |
| Storage Condition | Store at 4°C for 12 months. |
| Target | |
| Subcellular location | Extracellular |
| Synonyms | P2X1; ATP receptor; ATP receptor; H sapiens mRNA for ATP receptor; H.sapiens mRNA for ATP receptor; P2 RX1; P2RX1; P2RX1 protein; P2RX1_HUMAN; P2X purinoceptor 1; P2X receptor subunit 1; P2X1; P2X1 receptor; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 1; Purinergic receptor P2X ligand-gated ion channel 1; Purinergic receptor P2X1. |
| Background | The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IF(IHC-P) | 1:50-200 |
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