| Overview |
| bs-14241R-HRP |
| DEF8 Polyclonal Antibody, HRP Conjugated |
| WB, IHC-P, IHC-F |
| Human, Mouse, Rat |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic peptide derived from human DEF8 |
| 151-250/512 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 54849 |
| Q6ZN54 |
| DEF-8; Def8; Def 8; DEFI8_HUMAN; Differentially expressed in FDCP 8 homolog; FLJ20186; MGC104349. |
| DEF8 is a 512 amino acid protein that is expressed at highest levels in peripheral leukocytes. It is expressed as five isoforms as a result of alternative splicing events. The gene encoding DEF8 maps to chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
| Application Dilution |
| WB |
|
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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