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CCR4 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Rat
Overview
Catalog # bs-20788R-Biotin
Product Name CCR4 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Human, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CCR4
Immunogen Range 171-220/360
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1233
Swiss Prot P51679
Subcellular location Cell membrane
Synonyms CC chemokine receptor 4; chemokine (C-C motif) receptor 4; CC-CKR-4; CCR-4; CD194; CHEMOKINE CC4 RECEPTOR; CHEMR1; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5; LESTR; MGC151418; MGC88293; nocturnin, Sdf1r; chemokine C C motif receptor 4; ChemR13; CCR4_HUMAN; C-C chemokine receptor type 4; K5-5; CD 194; CD-194.
Background High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500