Overview |
bs-22037R-Biotin |
HOXD10 Polyclonal Antibody, Biotin Conjugated |
IHC-P, IHC-F |
Rat |
Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human HOXD10 |
111-210/340 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
3236 |
P28358 |
Nucleus |
Homeo box D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E; Homeobox protein Hox-D10; Hox 4.5; Hox 4D; Hox 4E; HOX4D; HOXD10; HXD10; HXD10_HUMAN; Hox 5.3. |
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
Application Dilution |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |