| Overview |
| bs-22608R-Biotin |
| IL-23R Polyclonal Antibody, Biotin Conjugated |
| WB |
| Human |
| Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human IL-23R |
| 231-330/629 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 149233 |
| Q5VWK5 |
| Cell membrane |
| IL23 Receptor; IL-23R; IL23R; interleukin 23 receptor; IL 23R; IL-23 receptor; IL23R_HUMAN; Interleukin-23 receptor. |
| Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3. |
| Application Dilution |
| WB |
1:300-5000 |
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