KLRC Family Polyclonal Antibody

Applications

  • ELISA
  • FCM
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Others
  • Monkey

Predicted Reactivity

  • Human
Overview
Catalog # bs-2416R
Product Name KLRC Family Polyclonal Antibody
Applications ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Others, Monkey
Predicted Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human NKG2C
Immunogen Range 51-150/231
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 3822
Swiss Prot P26717
Subcellular location Cell membrane
Synonyms KLRC1; NKG2-A/NKG2-B type II integral membrane protein; CD159a; NKG2-A/B-activating NK receptor; NK cell receptor A; NKG2A; NKG2B; KLRC2; NKG2-C type II integral membrane protein; CD159c; NK cell receptor C; NKG2-C-activating NK receptor; NKG2C; KLRC3; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor; NKG2E; KLRC4; NKG2-F type II integral membrane protein; NK cell receptor F; NKG2-F-activating NK receptor; NKG2F.
Background Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.
Application Dilution
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200