Overview |
bs-2736R-Cy5 |
IRS-1(Ser307) Polyclonal Antibody, Cy5 Conjugated |
FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
This phosphorylation site is homologous to Ser302 in Mouse and Rat. |
Human, Mouse, Rat, Goat |
Dog, Cow, Pig, Horse, Rabbit |
Specifications |
Cy5 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser307 [TE(p-S)IT] |
Ser307 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3667 |
P35568 |
Cell membrane |
HIRS-1; Insulin receptor substrate 1; IRS-1; IRS1 |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). |
Application Dilution |
FCM |
1:20-100 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |