| Overview |
| bs-3181R-Biotin |
| HSP90 alpha (Thr5 + Thr7) Antibody, Biotin Conjugated |
| WB, ELISA, IHC-P, IHC-F |
| These phosphorylation sites are homologous across the listed species. |
| Human, Mouse |
| Rat, Pig, Rabbit |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human HSP90 around the phosphorylation site of Thr5/7 |
| Thr5 + Thr7 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 3320 |
| P07900 |
| Cytoplasm, Nucleus |
| EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38; HSP90AA1 |
| Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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