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epithelial Sodium Channel gamma Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Rabbit
Overview
Catalog # bs-4263R-Biotin
Product Name epithelial Sodium Channel gamma Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ENaCg
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 6340
Swiss Prot P51170
Subcellular location Cell membrane
Synonyms PHA1; BESC3; ENaCg; SCNEG; ENaCgamma; Amiloride-sensitive sodium channel subunit gamma; Epithelial Na(+) channel subunit gamma; Gamma-ENaC; Gamma-NaCH; Nonvoltage-gated sodium channel 1 subunit gamma; SCNN1G
Background Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400