| Overview |
| bs-51003R |
| TBP (2C9) Monoclonal Antibody |
| WB |
| Human, Mouse |
| Specifications |
| Unconjugated |
| Mouse |
| Monoclonal antibody raised in mouse against the amino-terminal domain of human TBP (TATA box binding protein). |
| Monoclonal |
| 2C9 |
| IgG1 |
| 8ug/ul |
| Monoclonal antibody in PBS containing 0.05% azide; purified by ammonium sulphate precipitation followed by dialysis |
| PBS with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 6908 |
| P20226 |
| GTF2D, GTF2D1, SCA17, TF2D, TFIID |
| General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed:26638071). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription (PubMed:15970593). The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. |
| Application Dilution |
| WB |
1:300-5000 |
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