Jarid1b Polyclonal Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Mouse
Overview
Catalog # bs-51067R
Product Name Jarid1b Polyclonal Antibody
Applications WB, ELISA
Reactivity Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Polyclonal antibody raised in rabbit against mouse Jarid1b, using a KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein
Clonality Polyclonal
Isotype Not determined
Concentration Not Determined
Purification Whole antiserum from rabbit containing 0.05% azide
Storage Buffer Serum with 0.05% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 10765
Swiss Prot Q9UGL1
Synonyms CT31, PLU1, PUT1, RBBP2H1, RBP2-like
Background Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Application Dilution
WB 1:300-5000
ELISA 1:500-1000