PAPD5 Polyclonal Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-51073R
Product Name PAPD5 Polyclonal Antibody
Applications WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Polyclonal antibody raised in rabbit against human PAPD5 (PAP associated domain containing 5), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein
Clonality Polyclonal
Isotype Not determined
Concentration Not Determined
Purification Whole antiserum from rabbit containing 0.05% azide
Storage Buffer Serum with 0.05% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 64282
Swiss Prot Q8NDF8
Synonyms Non-canonical poly(A) RNA polymerase PAPD5, PAPD5, TRF4-2, TUTase 3, PAP-associated domain-containing protein 5
Background Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
Application Dilution
WB 1:300-5000